Journal of Anesthesiology and Clinical Research https://hmpublisher.com/index.php/JACR <p><strong>Journal of Anesthesiology and Clinical Research/JACR&nbsp;</strong> is a scientific journal,&nbsp;includes original research, review article, case report, and correspondence, that focuses on&nbsp;anesthesiology; pain management; intensive care; emergency medicine; disaster management; pharmacology; physiology; clinical practice research; health research and palliative medicine. This journal is a peer-reviewed journal established to improve the understanding of factors involved in anesthesiology and emergency medicine.</p> <p>JACR is published by &nbsp;<a href="https://cattleyacenter.id/" target="_blank" rel="noopener">CMHC (Research &amp; Sains Center)</a>&nbsp;and <a href="https://cattleyapublicationservices.com/hanifmedisiana/" target="_blank" rel="noopener">HM Publisher</a>. The journal is intended for scientists, clinicians, and professionals in anesthesiology, emergency, and related sciences. We welcome contributions from specialists in academia, industry, clinical practice, public health, and pharmacy, as well as from specialists in economics, social sciences, and other disciplines. JACR has <a href="https://issn.brin.go.id/terbit/detail/1598861996" target="_blank" rel="noopener">Electronic ISSN (eISSN): 2745-9497</a>. JACR also has&nbsp;<a href="https://portal.issn.org/resource/ISSN/2745-9497#" target="_blank" rel="noopener">International ISSN (ROAD) 2745-9497</a>.</p> HM Publisher en-US Journal of Anesthesiology and Clinical Research 2745-9497 Emergency General Anesthesia with Rapid Sequence Intubation for Cesarean Delivery in Severe Eclampsia Complicated by Pulmonary Edema and Premature Rupture of Membranes: A Multidisciplinary Critical Care Case Report https://hmpublisher.com/index.php/JACR/article/view/892 <p style="font-weight: 400;"><strong>Introduction: </strong>Eclampsia complicated by acute pulmonary edema is a life-threatening obstetric emergency that demands rapid, coordinated multidisciplinary intervention. Premature rupture of membranes (PROM) coexisting with refractory eclamptic seizures and respiratory failure further heightens maternal-fetal risk and complicates anesthetic decision-making. Optimal management requires individualized airway strategy, aggressive seizure control, and meticulous fluid balance under intensive care. &nbsp;</p> <p style="font-weight: 400;"><strong>Case presentation: </strong>A 28-year-old primigravida at term was referred from the emergency department after two generalized tonic-clonic seizures (5 minutes each), with severe hypertension (168/95 mmHg), tachypnea (RR 30/min), Glasgow Coma Scale 12 (sopor), bilateral basal rales, and oxygen desaturation to 92% on room air. Laboratory studies showed proteinuria +2, elevated transaminases (SGOT 62 U/L), and a PaO₂/FiO₂ ratio of 423 mmHg consistent with non-cardiogenic pulmonary edema. Emergency cesarean delivery was performed under general anesthesia with rapid sequence intubation (lidocaine-dexamethasone pretreatment, ketamine-propofol induction, rocuronium paralysis). A live male neonate (3420 g, APGAR 7-8-9) was delivered; surgery duration was 45 minutes. In the ICU, lung-protective mechanical ventilation, continuous furosemide infusion (5 mg/h, negative fluid balance strategy), and escalating multimodal anticonvulsant therapy (magnesium sulfate, midazolam, phenytoin) for refractory seizures were employed. The patient was extubated after 16 seizure-free hours, transferred to the ward on day 3, and discharged with her infant on day 4. &nbsp;</p> <p style="font-weight: 400;"><strong>Conclusion: </strong>Early recognition of eclampsia with pulmonary edema, individualized rapid sequence intubation general anesthesia, multimodal seizure control, and aggressive negative fluid balance under multidisciplinary critical care can yield favorable maternal-neonatal outcomes even in resource-constrained settings.</p> Muhammad Ibrahim Propan Hanggada Satyamakti Mubarak Copyright (c) 2026 Muhammad Ibrahim, Propan Hanggada Satyamakti Mubarak https://creativecommons.org/licenses/by-nc-sa/4.0 2026-05-11 2026-05-11 7 2 1256 1269 10.37275/jacr.v7i2.892