Pathogenesis Aspects of Microvascular Complications in Diabetic Retinopathy: Narrative Literature Review

Authors

  • Olga Simó-Servat Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain / Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ICSIII), Madrid, Spain
  • Cristina Hernández Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain / Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ICSIII), Madrid, Spain
  • Rafael Simó Diabetes and Metabolism Research Unit, Vall d’Hebron Research Institute, Barcelona, Spain / Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ICSIII), Madrid, Spain

DOI:

https://doi.org/10.37275/amcr.v3i2.197

Keywords:

Microvascular complications, Diabetic retinopathy, Mechanism

Abstract

Chronic hyperglycemic conditions in diabetes mellitus can cause changes that result in chronic complications, both macrovascular and microvascular. There are several mechanisms thought to cause microvascular damage and retinopathy in diabetes, namely the polyol pathway, formation of advanced glycation end products (AGE), activation of protein kinase C (PKC), oxidative stress, and increased activity of the hexosamine pathway.

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Published

2022-04-12

Issue

Vol. 3 No. 2 (2022): Archives of The Medicine and Case Reports

Section

Articles

License

Archives of The Medicine and Case Reports (AMCR) allow the author(s) to hold the copyright without restrictions and  allow the author(s) to retain publishing rights without restrictions, also the owner of the commercial rights to the article  is  the author.

How to Cite

Pathogenesis Aspects of Microvascular Complications in Diabetic Retinopathy: Narrative Literature Review. (2022). Archives of The Medicine and Case Reports, 3(2), 267-271. https://doi.org/10.37275/amcr.v3i2.197

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