Antioxidant Activity of Leucaena leucocephala Lmk.de Wit. N-Hexane Fraction
DOI:
https://doi.org/10.37275/oaijmr.v3i1.286Keywords:
Antioxidant, DPPH, IC50, Leucaena leucocephala, N-hexane fractionAbstract
Antioxidants are chemical compounds that can neutralize free radical agents. These compounds work by donating electrons to achieve a stable form, thereby inhibiting the oxidative mechanisms that cause degenerative disease. Lamtoro seeds contain many active compounds that can be used as a source of natural antioxidants and antibacterials. This study aimed to determine the antioxidant effect of the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk. de Wit.). This study is an in vitro experimental study. The object of study was the n-hexane fraction of lamtoro seeds, where antioxidant activity was examined using the DPPH method. Analysis was performed using a UV-Vis spectrophotometer. The n-hexane fraction contained a total flavonoid content of 9.224% and had antioxidant activity with an lC50 value of 67.94 ppm. In conclusion, the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk.de Wit.) has strong antioxidant activity.
Authors
- Ricka Islamiyati1*
- Yanulia Handayani1
- Kadar Ismah1
- Gendis Purno Yudanti1
- Heni Setyoningsih1
- Sri Fitrianingsih1
- 1Bachelor of Pharmacy Study Program, ITEKES Cendekia Utama Kudus, Kudus, Indonesia
Corresponding author Ricka Islamiyati — rickaislamiyati494@gmail.com
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